The 100,000 Genomes Project

The 100,000 Genomes Project aims to create an entirely new medical service based on genomic information for NHS patients.

NUH has joined with hospitals in Leicester, Cambridge and Norwich to form the East of England NHS Genomic Medicine Centre (NHS GMC), one of eleven centres in England designated to drive the national 100,000 Genomes Project. 

The project will begin by looking at 100,000 genetic codes from people who have a rare disease or a common cancer. 

The results will be linked with medical histories and stored securely. By doing this the project aims to:

  • Better understand the cause of rare diseases and cancers
  • Discover why some people get ill and others don’t
  • Learn the best way to use genetic codes to help people in the NHS
  • Support doctors and healthcare companies to develop new treatments and ways of diagnosing disease 

The East of England NHS GMC aims to gather 9,000 samples (6,000 for rare diseases and 3,000 for cancer). NUH will contribute approximately 3,000 samples to the project and more than 2,500 patients and relatives will take part.  


Taking part - what is involved

  • Discussion: Please talk to your doctor or nurse about your suitability to take part. They will refer you to the project team if you are eligible
  • Information: The project team will contact you to explain more about the project to you and answer any questions you might have
  • Appointment: If you wish to participate an appointment will be booked for you at the Genomic Medicine Centre, based at Nottingham City Hospital. If possible, we would also like both biological parents or other close blood relatives to attend. At the appointment we will ask everyone to consent to be part of the project before collecting some blood samples
  • Feedback: Results will be fed back to you as they become available


Get involved

For more information about the 100,000 Genomes Project and to get involved please talk to your consultant or contact Nicola McMaster, Programme Manager on 0115 969 1169 ext 56509 or email

NUH Genomic Medicine Centre
The David Evans Medical Research Centre
City Campus
Hucknall Road, Nottingham, NG5 1PB